BDBM50137837 8-Oxo-8-(4-pyridin-3-yl-phenyl)-octanoic acid (2-amino-phenyl)-amide::CHEMBL420998

SMILES: Nc1ccccc1NC(=O)CCCCCCC(=O)c1ccc(cc1)-c1cccnc1

InChI Key: InChIKey=FNFQNQNCCZPBLG-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137837   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase (Homo sapiens (Human))	BDBM50137837 (8-Oxo-8-(4-pyridin-3-yl-phenyl)-octanoic acid (2-a...) Show SMILES Nc1ccccc1NC(=O)CCCCCCC(=O)c1ccc(cc1)-c1cccnc1 Show InChI InChI=1S/C25H27N3O2/c26-22-9-5-6-10-23(22)28-25(30)12-4-2-1-3-11-24(29)20-15-13-19(14-16-20)21-8-7-17-27-18-21/h5-10,13-18H,1-4,11-12,26H2,(H,28,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Effect on induced hyperacetylation of histones in whole cells				Bioorg Med Chem Lett 14: 283-7 (2003) BindingDB Entry DOI: 10.7270/Q2BV7G17
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50137837 (8-Oxo-8-(4-pyridin-3-yl-phenyl)-octanoic acid (2-a...) Show SMILES Nc1ccccc1NC(=O)CCCCCCC(=O)c1ccc(cc1)-c1cccnc1 Show InChI InChI=1S/C25H27N3O2/c26-22-9-5-6-10-23(22)28-25(30)12-4-2-1-3-11-24(29)20-15-13-19(14-16-20)21-8-7-17-27-18-21/h5-10,13-18H,1-4,11-12,26H2,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).				Bioorg Med Chem Lett 14: 283-7 (2003) BindingDB Entry DOI: 10.7270/Q2BV7G17
					More data for this Ligand-Target Pair