BDBM50137843 8-Biphenyl-3-yl-8-oxo-octanoic acid (2-amino-phenyl)-amide::CHEMBL317718
SMILES: Nc1ccccc1NC(=O)CCCCCCC(=O)c1cccc(c1)-c1ccccc1
InChI Key: InChIKey=NHHIAZBCVUTFQI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50137843 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Histone deacetylase
(Homo sapiens (Human)) | BDBM50137843
(8-Biphenyl-3-yl-8-oxo-octanoic acid (2-amino-pheny...)Show SMILES Nc1ccccc1NC(=O)CCCCCCC(=O)c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C26H28N2O2/c27-23-15-8-9-16-24(23)28-26(30)18-7-2-1-6-17-25(29)22-14-10-13-21(19-22)20-11-4-3-5-12-20/h3-5,8-16,19H,1-2,6-7,17-18,27H2,(H,28,30) | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a |
MethylGene Inc.
Curated by ChEMBL
| Assay Description
Effect on induced hyperacetylation of histones in whole cells |
Bioorg Med Chem Lett 14: 283-7 (2003)
BindingDB Entry DOI: 10.7270/Q2BV7G17 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50137843
(8-Biphenyl-3-yl-8-oxo-octanoic acid (2-amino-pheny...)Show SMILES Nc1ccccc1NC(=O)CCCCCCC(=O)c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C26H28N2O2/c27-23-15-8-9-16-24(23)28-26(30)18-7-2-1-6-17-25(29)22-14-10-13-21(19-22)20-11-4-3-5-12-20/h3-5,8-16,19H,1-2,6-7,17-18,27H2,(H,28,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc.
Curated by ChEMBL
| Assay Description
Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1). |
Bioorg Med Chem Lett 14: 283-7 (2003)
BindingDB Entry DOI: 10.7270/Q2BV7G17 |
More data for this
Ligand-Target Pair | |
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