BDBM50137862 (Z)-4-[3-(5-Bromo-2-cyano-benzyloxy)-phenyl]-2-hydroxy-4-oxo-but-2-enoic acid::CHEMBL362185

SMILES: OC(=O)C(=O)CC(=O)c1cccc(OCc2cc(Br)ccc2C#N)c1

InChI Key: InChIKey=NSWHZSKSOBTQQQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137862   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50137862 ((Z)-4-[3-(5-Bromo-2-cyano-benzyloxy)-phenyl]-2-hyd...) Show SMILES OC(=O)C(=O)CC(=O)c1cccc(OCc2cc(Br)ccc2C#N)c1 Show InChI InChI=1S/C18H12BrNO5/c19-14-5-4-12(9-20)13(6-14)10-25-15-3-1-2-11(7-15)16(21)8-17(22)18(23)24/h1-7H,8,10H2,(H,23,24)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	7.5	n/a
University of Rome La Sapienza Curated by ChEMBL					Assay Description Inhibitory concentration against NS5B HCV polymerase using [alpha-32P]UTP as radioligand (30 degree C for 2 h, at pH 7.5 with Tris-HCl buffer)				J Med Chem 48: 6304-14 (2005) Article DOI: 10.1021/jm0504454 BindingDB Entry DOI: 10.7270/Q2T43SNM
					More data for this Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50137862 ((Z)-4-[3-(5-Bromo-2-cyano-benzyloxy)-phenyl]-2-hyd...) Show SMILES OC(=O)C(=O)CC(=O)c1cccc(OCc2cc(Br)ccc2C#N)c1 Show InChI InChI=1S/C18H12BrNO5/c19-14-5-4-12(9-20)13(6-14)10-25-15-3-1-2-11(7-15)16(21)8-17(22)18(23)24/h1-7H,8,10H2,(H,23,24)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Italy. Vinc Curated by ChEMBL					Assay Description Inhibitory activity against Hepatitis C virus RNA dependent RNA polymerase nonstructural protein 5B				J Med Chem 47: 14-7 (2003) Article DOI: 10.1021/jm0342109 BindingDB Entry DOI: 10.7270/Q2736QB8
					More data for this Ligand-Target Pair