BDBM50137872 2,4-dioxo-4-{3-[(phenylsulfonyl)amino]phenyl}butanoic acid::4-(3-Benzenesulfonylamino-phenyl)-2,4-dioxo-butyric acid::CHEMBL175533

SMILES: OC(=O)C(=O)CC(=O)c1cccc(NS(=O)(=O)c2ccccc2)c1

InChI Key: InChIKey=PBXNBVGNXBZXSA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137872   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50137872 (2,4-dioxo-4-{3-[(phenylsulfonyl)amino]phenyl}butan...) Show SMILES OC(=O)C(=O)CC(=O)c1cccc(NS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C16H13NO6S/c18-14(10-15(19)16(20)21)11-5-4-6-12(9-11)17-24(22,23)13-7-2-1-3-8-13/h1-9,17H,10H2,(H,20,21)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Italy. Vinc Curated by ChEMBL					Assay Description Inhibitory activity against Hepatitis C virus RNA dependent RNA polymerase nonstructural protein 5B				J Med Chem 47: 14-7 (2003) Article DOI: 10.1021/jm0342109 BindingDB Entry DOI: 10.7270/Q2736QB8
					More data for this Ligand-Target Pair