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BDBM50137884 (1,1-Difluoro-2-{3'-[(naphthalen-1-ylmethyl)-carbamoyl]-biphenyl-4-yl}-2-oxo-ethyl)-phosphonic acid::(1,1-Difluoro-2-{3'-[(naphthalen-1-ylmethyl)-carbamoyl]-biphenyl-4-yl}-2-oxoethyl)-phosphonic acid::CHEMBL178015

SMILES: OP(O)(=O)C(F)(F)C(=O)c1ccc(cc1)-c1cccc(c1)C(=O)NCc1cccc2ccccc12

InChI Key: InChIKey=CHXYLZFHEGHFPJ-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137884   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Replication protein E1


(Human papillomavirus type 11)
BDBM50137884
PNG
((1,1-Difluoro-2-{3'-[(naphthalen-1-ylmethyl)-carba...)
Show SMILES OP(O)(=O)C(F)(F)C(=O)c1ccc(cc1)-c1cccc(c1)C(=O)NCc1cccc2ccccc12
Show InChI InChI=1S/C26H20F2NO5P/c27-26(28,35(32,33)34)24(30)19-13-11-17(12-14-19)20-7-4-8-21(15-20)25(31)29-16-22-9-3-6-18-5-1-2-10-23(18)22/h1-15H,16H2,(H,29,31)(H2,32,33,34)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 740n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd.

Curated by ChEMBL


Assay Description
Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicase


J Med Chem 47: 18-21 (2003)


Article DOI: 10.1021/jm034206x
BindingDB Entry DOI: 10.7270/Q23F4P2Q
More data for this
Ligand-Target Pair