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BDBM50137925 CHEMBL368100::[3'-((R)-1-Phenyl-ethylcarbamoyl)-biphenyl-4-sulfonyl]-acetic acid::[3'-(1-(R)-phenyl-ethylcarbamoyl)-biphenyl-4-sulfonyl]-acetic acid

SMILES: C[C@@H](NC(=O)c1cccc(c1)-c1ccc(cc1)S(=O)(=O)CC(O)=O)c1ccccc1

InChI Key: InChIKey=PIOOGZRVKAYOEW-MRXNPFEDSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137925   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Replication protein E1


(Human papillomavirus type 11)
BDBM50137925
PNG
(CHEMBL368100 | [3'-((R)-1-Phenyl-ethylcarbamoyl)-b...)
Show SMILES C[C@@H](NC(=O)c1cccc(c1)-c1ccc(cc1)S(=O)(=O)CC(O)=O)c1ccccc1 |r|
Show InChI InChI=1S/C23H21NO5S/c1-16(17-6-3-2-4-7-17)24-23(27)20-9-5-8-19(14-20)18-10-12-21(13-11-18)30(28,29)15-22(25)26/h2-14,16H,15H2,1H3,(H,24,27)(H,25,26)/t16-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 43n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd.

Curated by ChEMBL


Assay Description
Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicase


J Med Chem 47: 18-21 (2003)


Article DOI: 10.1021/jm034206x
BindingDB Entry DOI: 10.7270/Q23F4P2Q
More data for this
Ligand-Target Pair