BDBM50137998 3-Benzylamino-10-keto-N-cyclobutylmethylmorphinan::CHEMBL49106

SMILES: O=C(Nc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1)c1ccccc1

InChI Key: InChIKey=HMZOMKWKBKHNRX-YRLRHBCXSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50137998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (GUINEA PIG)	BDBM50137998 (3-Benzylamino-10-keto-N-cyclobutylmethylmorphinan ...) Show SMILES O=C(Nc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1)c1ccccc1 Show InChI InChI=1S/C28H32N2O2/c31-26-22-13-12-21(29-27(32)20-9-2-1-3-10-20)17-24(22)28-14-5-4-11-23(28)25(26)30(16-15-28)18-19-7-6-8-19/h1-3,9-10,12-13,17,19,23,25H,4-8,11,14-16,18H2,(H,29,32)/t23-,25-,28+/m0/s1	UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity against opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brain membranes.				J Med Chem 47: 165-74 (2003) Article DOI: 10.1021/jm0304156 BindingDB Entry DOI: 10.7270/Q2KD1XB2
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50137998 (3-Benzylamino-10-keto-N-cyclobutylmethylmorphinan ...) Show SMILES O=C(Nc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1)c1ccccc1 Show InChI InChI=1S/C28H32N2O2/c31-26-22-13-12-21(29-27(32)20-9-2-1-3-10-20)17-24(22)28-14-5-4-11-23(28)25(26)30(16-15-28)18-19-7-6-8-19/h1-3,9-10,12-13,17,19,23,25H,4-8,11,14-16,18H2,(H,29,32)/t23-,25-,28+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.				J Med Chem 47: 165-74 (2003) Article DOI: 10.1021/jm0304156 BindingDB Entry DOI: 10.7270/Q2KD1XB2
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50137998 (3-Benzylamino-10-keto-N-cyclobutylmethylmorphinan ...) Show SMILES O=C(Nc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1)c1ccccc1 Show InChI InChI=1S/C28H32N2O2/c31-26-22-13-12-21(29-27(32)20-9-2-1-3-10-20)17-24(22)28-14-5-4-11-23(28)25(26)30(16-15-28)18-19-7-6-8-19/h1-3,9-10,12-13,17,19,23,25H,4-8,11,14-16,18H2,(H,29,32)/t23-,25-,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity against opioid receptor delta 1 using [3H]-naltrindole as radioligand in guinea pig brain membranes.				J Med Chem 47: 165-74 (2003) Article DOI: 10.1021/jm0304156 BindingDB Entry DOI: 10.7270/Q2KD1XB2
					More data for this Ligand-Target Pair