BindingDB logo
myBDB logout

BDBM50138620 CHEMBL155166::N-Cyclohexyl-2-{4-[(R)-2-hydroxy-3-(2-methyl-benzothiazol-5-yloxy)-propyl]-piperazin-1-yl}-acetamide

SMILES: Cc1nc2cc(OC[C@H](O)CN3CCN(CC(=O)NC4CCCCC4)CC3)ccc2s1

InChI Key: InChIKey=LECQEFOFEIRODW-LJQANCHMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50138620   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisomal acyl-coenzyme A oxidase 1


(Rattus norvegicus)
BDBM50138620
PNG
(CHEMBL155166 | N-Cyclohexyl-2-{4-[(R)-2-hydroxy-3-...)
Show SMILES Cc1nc2cc(OC[C@H](O)CN3CCN(CC(=O)NC4CCCCC4)CC3)ccc2s1
Show InChI InChI=1S/C23H34N4O3S/c1-17-24-21-13-20(7-8-22(21)31-17)30-16-19(28)14-26-9-11-27(12-10-26)15-23(29)25-18-5-3-2-4-6-18/h7-8,13,18-19,28H,2-6,9-12,14-16H2,1H3,(H,25,29)/t19-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 8.60E+3n/an/an/an/an/an/a



CV Therapeutics

Curated by ChEMBL


Assay Description
Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.


Bioorg Med Chem Lett 14: 549-52 (2003)


BindingDB Entry DOI: 10.7270/Q2GH9HD4
More data for this
Ligand-Target Pair