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BDBM50138631 CHEMBL153650::N-(3,4-Dichloro-phenyl)-2-{4-[(R)-2-hydroxy-3-(2-methyl-benzothiazol-5-yloxy)-propyl]-piperazin-1-yl}-acetamide

SMILES: Cc1nc2cc(OC[C@H](O)CN3CCN(CC(=O)Nc4ccc(Cl)c(Cl)c4)CC3)ccc2s1

InChI Key: InChIKey=YXYKTPNBPFSRSY-QGZVFWFLSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50138631   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Palmitoyl-CoA oxidase


(Rattus norvegicus)
BDBM50138631
PNG
(CHEMBL153650 | N-(3,4-Dichloro-phenyl)-2-{4-[(R)-2...)
Show SMILES Cc1nc2cc(OC[C@H](O)CN3CCN(CC(=O)Nc4ccc(Cl)c(Cl)c4)CC3)ccc2s1
Show InChI InChI=1S/C23H26Cl2N4O3S/c1-15-26-21-11-18(3-5-22(21)33-15)32-14-17(30)12-28-6-8-29(9-7-28)13-23(31)27-16-2-4-19(24)20(25)10-16/h2-5,10-11,17,30H,6-9,12-14H2,1H3,(H,27,31)/t17-/m1/s1
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CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 6.00E+3n/an/an/an/an/an/a



CV Therapeutics

Curated by ChEMBL


Assay Description
Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.


Bioorg Med Chem Lett 14: 549-52 (2003)

More data for this
Ligand-Target Pair