BDBM50139022 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-(2-ethoxy-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-amide::CHEMBL423619

SMILES: CCOc1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1

InChI Key: InChIKey=UXFNZCRYDMKXGJ-KAYWLYCHSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139022   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50139022 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES CCOc1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1 Show InChI InChI=1S/C31H35ClN4O3/c1-2-39-29-10-6-5-9-28(29)35-15-17-36(18-16-35)31(38)27(19-22-11-13-25(32)14-12-22)34-30(37)26-20-23-7-3-4-8-24(23)21-33-26/h3-14,26-27,33H,2,15-21H2,1H3,(H,34,37)/t26-,27-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP release				J Med Chem 47: 744-55 (2004) Article DOI: 10.1021/jm0304109 BindingDB Entry DOI: 10.7270/Q2DJ5F21
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50139022 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES CCOc1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1 Show InChI InChI=1S/C31H35ClN4O3/c1-2-39-29-10-6-5-9-28(29)35-15-17-36(18-16-35)31(38)27(19-22-11-13-25(32)14-12-22)34-30(37)26-20-23-7-3-4-8-24(23)21-33-26/h3-14,26-27,33H,2,15-21H2,1H3,(H,34,37)/t26-,27-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Agonistic potency of the compound towards human melanocortin 4 receptor, determined by 50% maximum cAMP release				J Med Chem 47: 744-55 (2004) Article DOI: 10.1021/jm0304109 BindingDB Entry DOI: 10.7270/Q2DJ5F21
					More data for this Ligand-Target Pair