BDBM50139029 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ((R)-1-(4-chloro-benzyl)-2-{4-[2-(2-methyl-imidazol-1-ylmethyl)-phenyl]-piperazin-1-yl}-2-oxo-ethyl)-amide::CHEMBL164857

SMILES: Cc1nccn1Cc1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1

InChI Key: InChIKey=XLQVBCBFSNNDIK-FIRIVFDPSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139029   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50139029 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Cc1nccn1Cc1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1 Show InChI InChI=1S/C34H37ClN6O2/c1-24-36-14-15-41(24)23-28-8-4-5-9-32(28)39-16-18-40(19-17-39)34(43)31(20-25-10-12-29(35)13-11-25)38-33(42)30-21-26-6-2-3-7-27(26)22-37-30/h2-15,30-31,37H,16-23H2,1H3,(H,38,42)/t30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP release				J Med Chem 47: 744-55 (2004) Article DOI: 10.1021/jm0304109 BindingDB Entry DOI: 10.7270/Q2DJ5F21
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50139029 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Cc1nccn1Cc1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1 Show InChI InChI=1S/C34H37ClN6O2/c1-24-36-14-15-41(24)23-28-8-4-5-9-32(28)39-16-18-40(19-17-39)34(43)31(20-25-10-12-29(35)13-11-25)38-33(42)30-21-26-6-2-3-7-27(26)22-37-30/h2-15,30-31,37H,16-23H2,1H3,(H,38,42)/t30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Agonistic potency of the compound towards human melanocortin 4 receptor, determined by 50% maximum cAMP release				J Med Chem 47: 744-55 (2004) Article DOI: 10.1021/jm0304109 BindingDB Entry DOI: 10.7270/Q2DJ5F21
					More data for this Ligand-Target Pair