null

SMILES: C[C@@H](NC(=O)c1cccc(c1)C#N)C(=O)N1CCN(CCCOc2ccc(-c3noc(CC4CCCC4)n3)c(F)c2)CC1

InChI Key: InChIKey=DGZKCXDXTXTNRW-JOCHJYFZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139297 (2-(3-Cyano-phenyl)-N-[(R)-2-(4-{3-[4-(5-cyclopenty...) Show SMILES C[C@@H](NC(=O)c1cccc(c1)C#N)C(=O)N1CCN(CCCOc2ccc(-c3noc(CC4CCCC4)n3)c(F)c2)CC1 Show InChI InChI=1S/C32H37FN6O4/c1-22(35-31(40)25-9-4-8-24(18-25)21-34)32(41)39-15-13-38(14-16-39)12-5-17-42-26-10-11-27(28(33)20-26)30-36-29(43-37-30)19-23-6-2-3-7-23/h4,8-11,18,20,22-23H,2-3,5-7,12-17,19H2,1H3,(H,35,40)/t22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity for rat histamine H3 receptor on rat cortical cells				Bioorg Med Chem Lett 14: 673-6 (2004) BindingDB Entry DOI: 10.7270/Q2H994MH
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139297 (2-(3-Cyano-phenyl)-N-[(R)-2-(4-{3-[4-(5-cyclopenty...) Show SMILES C[C@@H](NC(=O)c1cccc(c1)C#N)C(=O)N1CCN(CCCOc2ccc(-c3noc(CC4CCCC4)n3)c(F)c2)CC1 Show InChI InChI=1S/C32H37FN6O4/c1-22(35-31(40)25-9-4-8-24(18-25)21-34)32(41)39-15-13-38(14-16-39)12-5-17-42-26-10-11-27(28(33)20-26)30-36-29(43-37-30)19-23-6-2-3-7-23/h4,8-11,18,20,22-23H,2-3,5-7,12-17,19H2,1H3,(H,35,40)/t22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity for human histamine H3 receptor on human colon cells				Bioorg Med Chem Lett 14: 673-6 (2004) BindingDB Entry DOI: 10.7270/Q2H994MH
					More data for this Ligand-Target Pair