null

SMILES: C[C@@H](NC(=O)c1ccco1)C(=O)N1CCCN(CCCOc2ccc(-c3noc(CC4CCCC4)n3)c(F)c2)CC1

InChI Key: InChIKey=IDWWRQHTZWPOJT-OAQYLSRUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139326   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139326 (CHEMBL349692 | Furan-2-carboxylic acid [(R)-2-(4-{...) Show SMILES C[C@@H](NC(=O)c1ccco1)C(=O)N1CCCN(CCCOc2ccc(-c3noc(CC4CCCC4)n3)c(F)c2)CC1 Show InChI InChI=1S/C30H38FN5O5/c1-21(32-29(37)26-9-4-17-40-26)30(38)36-14-5-12-35(15-16-36)13-6-18-39-23-10-11-24(25(31)20-23)28-33-27(41-34-28)19-22-7-2-3-8-22/h4,9-11,17,20-22H,2-3,5-8,12-16,18-19H2,1H3,(H,32,37)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity for rat histamine H3 receptor on rat cortical cells				Bioorg Med Chem Lett 14: 673-6 (2004) BindingDB Entry DOI: 10.7270/Q2H994MH
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139326 (CHEMBL349692 | Furan-2-carboxylic acid [(R)-2-(4-{...) Show SMILES C[C@@H](NC(=O)c1ccco1)C(=O)N1CCCN(CCCOc2ccc(-c3noc(CC4CCCC4)n3)c(F)c2)CC1 Show InChI InChI=1S/C30H38FN5O5/c1-21(32-29(37)26-9-4-17-40-26)30(38)36-14-5-12-35(15-16-36)13-6-18-39-23-10-11-24(25(31)20-23)28-33-27(41-34-28)19-22-7-2-3-8-22/h4,9-11,17,20-22H,2-3,5-8,12-16,18-19H2,1H3,(H,32,37)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity for human histamine H3 receptor on human colon cells				Bioorg Med Chem Lett 14: 673-6 (2004) BindingDB Entry DOI: 10.7270/Q2H994MH
					More data for this Ligand-Target Pair