null

SMILES: C[C@@H](NC(=O)C(C)(C)C)C(=O)N1CCCN(CCCOc2ccc(-c3noc(CC4CCCC4)n3)c(F)c2)CC1

InChI Key: InChIKey=WKWJUQTTZUDKNB-OAQYLSRUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139336   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139336 (CHEMBL159085 | N-[(R)-2-(4-{3-[4-(5-Cyclopentylmet...) Show SMILES C[C@@H](NC(=O)C(C)(C)C)C(=O)N1CCCN(CCCOc2ccc(-c3noc(CC4CCCC4)n3)c(F)c2)CC1 Show InChI InChI=1S/C30H44FN5O4/c1-21(32-29(38)30(2,3)4)28(37)36-15-7-13-35(16-17-36)14-8-18-39-23-11-12-24(25(31)20-23)27-33-26(40-34-27)19-22-9-5-6-10-22/h11-12,20-22H,5-10,13-19H2,1-4H3,(H,32,38)/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity for rat histamine H3 receptor on rat cortical cells				Bioorg Med Chem Lett 14: 673-6 (2004) BindingDB Entry DOI: 10.7270/Q2H994MH
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139336 (CHEMBL159085 | N-[(R)-2-(4-{3-[4-(5-Cyclopentylmet...) Show SMILES C[C@@H](NC(=O)C(C)(C)C)C(=O)N1CCCN(CCCOc2ccc(-c3noc(CC4CCCC4)n3)c(F)c2)CC1 Show InChI InChI=1S/C30H44FN5O4/c1-21(32-29(38)30(2,3)4)28(37)36-15-7-13-35(16-17-36)14-8-18-39-23-11-12-24(25(31)20-23)27-33-26(40-34-27)19-22-9-5-6-10-22/h11-12,20-22H,5-10,13-19H2,1-4H3,(H,32,38)/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity for human histamine H3 receptor on human colon cells				Bioorg Med Chem Lett 14: 673-6 (2004) BindingDB Entry DOI: 10.7270/Q2H994MH
					More data for this Ligand-Target Pair