null

SMILES: C[C@@H](NC(=O)c1ccco1)C(=O)N1CCN(CCCOc2ccc(C(=O)C3CC3)c(F)c2)CC1

InChI Key: InChIKey=VTQGCRAVMHGNKF-QGZVFWFLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139348   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139348 (CHEMBL161479 | Furan-2-carboxylic acid ((R)-2-{4-[...) Show SMILES C[C@@H](NC(=O)c1ccco1)C(=O)N1CCN(CCCOc2ccc(C(=O)C3CC3)c(F)c2)CC1 Show InChI InChI=1S/C25H30FN3O5/c1-17(27-24(31)22-4-2-14-34-22)25(32)29-12-10-28(11-13-29)9-3-15-33-19-7-8-20(21(26)16-19)23(30)18-5-6-18/h2,4,7-8,14,16-18H,3,5-6,9-13,15H2,1H3,(H,27,31)/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity for rat histamine H3 receptor on rat cortical cells				Bioorg Med Chem Lett 14: 673-6 (2004) BindingDB Entry DOI: 10.7270/Q2H994MH
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139348 (CHEMBL161479 | Furan-2-carboxylic acid ((R)-2-{4-[...) Show SMILES C[C@@H](NC(=O)c1ccco1)C(=O)N1CCN(CCCOc2ccc(C(=O)C3CC3)c(F)c2)CC1 Show InChI InChI=1S/C25H30FN3O5/c1-17(27-24(31)22-4-2-14-34-22)25(32)29-12-10-28(11-13-29)9-3-15-33-19-7-8-20(21(26)16-19)23(30)18-5-6-18/h2,4,7-8,14,16-18H,3,5-6,9-13,15H2,1H3,(H,27,31)/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity for human histamine H3 receptor on human colon cells				Bioorg Med Chem Lett 14: 673-6 (2004) BindingDB Entry DOI: 10.7270/Q2H994MH
					More data for this Ligand-Target Pair