null

SMILES: CN(C)CCSc1cccc(n1)C1(O)CCCCC1

InChI Key: InChIKey=NJQKIZFGISMHHC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139354   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139354 (1-[6-(2-Dimethylamino-ethylsulfanyl)-pyridin-2-yl]...) Show SMILES CN(C)CCSc1cccc(n1)C1(O)CCCCC1 Show InChI InChI=1S/C15H24N2OS/c1-17(2)11-12-19-14-8-6-7-13(16-14)15(18)9-4-3-5-10-15/h6-8,18H,3-5,9-12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50139354 (1-[6-(2-Dimethylamino-ethylsulfanyl)-pyridin-2-yl]...) Show SMILES CN(C)CCSc1cccc(n1)C1(O)CCCCC1 Show InChI InChI=1S/C15H24N2OS/c1-17(2)11-12-19-14-8-6-7-13(16-14)15(18)9-4-3-5-10-15/h6-8,18H,3-5,9-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50139354 (1-[6-(2-Dimethylamino-ethylsulfanyl)-pyridin-2-yl]...) Show SMILES CN(C)CCSc1cccc(n1)C1(O)CCCCC1 Show InChI InChI=1S/C15H24N2OS/c1-17(2)11-12-19-14-8-6-7-13(16-14)15(18)9-4-3-5-10-15/h6-8,18H,3-5,9-12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 2A receptor by the displacement of [3H]-Ketanserin radioligand from the cloned receptor expressed ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50139354 (1-[6-(2-Dimethylamino-ethylsulfanyl)-pyridin-2-yl]...) Show SMILES CN(C)CCSc1cccc(n1)C1(O)CCCCC1 Show InChI InChI=1S/C15H24N2OS/c1-17(2)11-12-19-14-8-6-7-13(16-14)15(18)9-4-3-5-10-15/h6-8,18H,3-5,9-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human dopamine receptor D2 by the displacement of [3H]-Spiperone radioligand from the cloned receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair