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SMILES: C[C@@H]1CC[C@@H](C)N1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C(=O)N1CCOCC1

InChI Key: InChIKey=BQAYROGJKLQKEO-WOJBJXKFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139383 ((4-{2-[2-((2R,5R)-2,5-Dimethyl-pyrrolidin-1-yl)-et...) Show SMILES C[C@@H]1CC[C@@H](C)N1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C27H32N2O3/c1-19-3-4-20(2)29(19)12-11-25-18-24-17-23(9-10-26(24)32-25)21-5-7-22(8-6-21)27(30)28-13-15-31-16-14-28/h5-10,17-20H,3-4,11-16H2,1-2H3/t19-,20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139383 ((4-{2-[2-((2R,5R)-2,5-Dimethyl-pyrrolidin-1-yl)-et...) Show SMILES C[C@@H]1CC[C@@H](C)N1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C27H32N2O3/c1-19-3-4-20(2)29(19)12-11-25-18-24-17-23(9-10-26(24)32-25)21-5-7-22(8-6-21)27(30)28-13-15-31-16-14-28/h5-10,17-20H,3-4,11-16H2,1-2H3/t19-,20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139383 ((4-{2-[2-((2R,5R)-2,5-Dimethyl-pyrrolidin-1-yl)-et...) Show SMILES C[C@@H]1CC[C@@H](C)N1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C27H32N2O3/c1-19-3-4-20(2)29(19)12-11-25-18-24-17-23(9-10-26(24)32-25)21-5-7-22(8-6-21)27(30)28-13-15-31-16-14-28/h5-10,17-20H,3-4,11-16H2,1-2H3/t19-,20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139383 ((4-{2-[2-((2R,5R)-2,5-Dimethyl-pyrrolidin-1-yl)-et...) Show SMILES C[C@@H]1CC[C@@H](C)N1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C27H32N2O3/c1-19-3-4-20(2)29(19)12-11-25-18-24-17-23(9-10-26(24)32-25)21-5-7-22(8-6-21)27(30)28-13-15-31-16-14-28/h5-10,17-20H,3-4,11-16H2,1-2H3/t19-,20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair