null

SMILES: O=C(N1CCOCC1)c1ccc(cc1)-c1ccc2oc(CCN3CCCCCC3)cc2c1

InChI Key: InChIKey=DCLOKKGTZFTADV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139385   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139385 (CHEMBL346562 | {4-[2-(2-Azepan-1-yl-ethyl)-benzofu...) Show SMILES O=C(N1CCOCC1)c1ccc(cc1)-c1ccc2oc(CCN3CCCCCC3)cc2c1 Show InChI InChI=1S/C27H32N2O3/c30-27(29-15-17-31-18-16-29)22-7-5-21(6-8-22)23-9-10-26-24(19-23)20-25(32-26)11-14-28-12-3-1-2-4-13-28/h5-10,19-20H,1-4,11-18H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139385 (CHEMBL346562 | {4-[2-(2-Azepan-1-yl-ethyl)-benzofu...) Show SMILES O=C(N1CCOCC1)c1ccc(cc1)-c1ccc2oc(CCN3CCCCCC3)cc2c1 Show InChI InChI=1S/C27H32N2O3/c30-27(29-15-17-31-18-16-29)22-7-5-21(6-8-22)23-9-10-26-24(19-23)20-25(32-26)11-14-28-12-3-1-2-4-13-28/h5-10,19-20H,1-4,11-18H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139385 (CHEMBL346562 | {4-[2-(2-Azepan-1-yl-ethyl)-benzofu...) Show SMILES O=C(N1CCOCC1)c1ccc(cc1)-c1ccc2oc(CCN3CCCCCC3)cc2c1 Show InChI InChI=1S/C27H32N2O3/c30-27(29-15-17-31-18-16-29)22-7-5-21(6-8-22)23-9-10-26-24(19-23)20-25(32-26)11-14-28-12-3-1-2-4-13-28/h5-10,19-20H,1-4,11-18H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139385 (CHEMBL346562 | {4-[2-(2-Azepan-1-yl-ethyl)-benzofu...) Show SMILES O=C(N1CCOCC1)c1ccc(cc1)-c1ccc2oc(CCN3CCCCCC3)cc2c1 Show InChI InChI=1S/C27H32N2O3/c30-27(29-15-17-31-18-16-29)22-7-5-21(6-8-22)23-9-10-26-24(19-23)20-25(32-26)11-14-28-12-3-1-2-4-13-28/h5-10,19-20H,1-4,11-18H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair