null

SMILES: O=C(N1CCOCC1)c1ccc(nc1)-c1ccc2oc(CCN3CCCC3)cc2c1

InChI Key: InChIKey=RRLCACGGDHPKNQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139392 (CHEMBL422360 | Morpholin-4-yl-{6-[2-(2-pyrrolidin-...) Show SMILES O=C(N1CCOCC1)c1ccc(nc1)-c1ccc2oc(CCN3CCCC3)cc2c1 Show InChI InChI=1S/C24H27N3O3/c28-24(27-11-13-29-14-12-27)19-3-5-22(25-17-19)18-4-6-23-20(15-18)16-21(30-23)7-10-26-8-1-2-9-26/h3-6,15-17H,1-2,7-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139392 (CHEMBL422360 | Morpholin-4-yl-{6-[2-(2-pyrrolidin-...) Show SMILES O=C(N1CCOCC1)c1ccc(nc1)-c1ccc2oc(CCN3CCCC3)cc2c1 Show InChI InChI=1S/C24H27N3O3/c28-24(27-11-13-29-14-12-27)19-3-5-22(25-17-19)18-4-6-23-20(15-18)16-21(30-23)7-10-26-8-1-2-9-26/h3-6,15-17H,1-2,7-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139392 (CHEMBL422360 | Morpholin-4-yl-{6-[2-(2-pyrrolidin-...) Show SMILES O=C(N1CCOCC1)c1ccc(nc1)-c1ccc2oc(CCN3CCCC3)cc2c1 Show InChI InChI=1S/C24H27N3O3/c28-24(27-11-13-29-14-12-27)19-3-5-22(25-17-19)18-4-6-23-20(15-18)16-21(30-23)7-10-26-8-1-2-9-26/h3-6,15-17H,1-2,7-14H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139392 (CHEMBL422360 | Morpholin-4-yl-{6-[2-(2-pyrrolidin-...) Show SMILES O=C(N1CCOCC1)c1ccc(nc1)-c1ccc2oc(CCN3CCCC3)cc2c1 Show InChI InChI=1S/C24H27N3O3/c28-24(27-11-13-29-14-12-27)19-3-5-22(25-17-19)18-4-6-23-20(15-18)16-21(30-23)7-10-26-8-1-2-9-26/h3-6,15-17H,1-2,7-14H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair