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SMILES: OC[C@@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C(=O)N1CCOCC1

InChI Key: InChIKey=QPELKPGNVCYMRF-QHCPKHFHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139408   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139408 ((4-{2-[2-((S)-2-Hydroxymethyl-pyrrolidin-1-yl)-eth...) Show SMILES OC[C@@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H30N2O4/c29-18-23-2-1-10-27(23)11-9-24-17-22-16-21(7-8-25(22)32-24)19-3-5-20(6-4-19)26(30)28-12-14-31-15-13-28/h3-8,16-17,23,29H,1-2,9-15,18H2/t23-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139408 ((4-{2-[2-((S)-2-Hydroxymethyl-pyrrolidin-1-yl)-eth...) Show SMILES OC[C@@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H30N2O4/c29-18-23-2-1-10-27(23)11-9-24-17-22-16-21(7-8-25(22)32-24)19-3-5-20(6-4-19)26(30)28-12-14-31-15-13-28/h3-8,16-17,23,29H,1-2,9-15,18H2/t23-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139408 ((4-{2-[2-((S)-2-Hydroxymethyl-pyrrolidin-1-yl)-eth...) Show SMILES OC[C@@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H30N2O4/c29-18-23-2-1-10-27(23)11-9-24-17-22-16-21(7-8-25(22)32-24)19-3-5-20(6-4-19)26(30)28-12-14-31-15-13-28/h3-8,16-17,23,29H,1-2,9-15,18H2/t23-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139408 ((4-{2-[2-((S)-2-Hydroxymethyl-pyrrolidin-1-yl)-eth...) Show SMILES OC[C@@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H30N2O4/c29-18-23-2-1-10-27(23)11-9-24-17-22-16-21(7-8-25(22)32-24)19-3-5-20(6-4-19)26(30)28-12-14-31-15-13-28/h3-8,16-17,23,29H,1-2,9-15,18H2/t23-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair