BDBM50139565 4-(5-{[3-(3-Fluoro-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-ylamino]-methyl}-imidazol-1-ylmethyl)-benzonitrile::CHEMBL165072

SMILES: Fc1cccc(CN2CCc3ccccc3C(NCc3cncn3Cc3ccc(cc3)C#N)C2=O)c1

InChI Key: InChIKey=VZYUPNNXYRHBMJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50139565   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50139565 (4-(5-{[3-(3-Fluoro-benzyl)-2-oxo-2,3,4,5-tetrahydr...) Show SMILES Fc1cccc(CN2CCc3ccccc3C(NCc3cncn3Cc3ccc(cc3)C#N)C2=O)c1 Show InChI InChI=1S/C29H26FN5O/c30-25-6-3-4-23(14-25)19-34-13-12-24-5-1-2-7-27(24)28(29(34)36)33-17-26-16-32-20-35(26)18-22-10-8-21(15-31)9-11-22/h1-11,14,16,20,28,33H,12-13,17-19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of farnesyltransferase				Bioorg Med Chem Lett 14: 767-71 (2004) BindingDB Entry DOI: 10.7270/Q2348JSW
					More data for this Ligand-Target Pair