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SMILES: O=C1[C@H](CCCCN1Cc1ccccc1)NCc1cncn1Cc1ccc(cc1)C#N

InChI Key: InChIKey=UOOPOGXXNZHSPG-DEOSSOPVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50139568   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50139568
PNG
(4-{5-[((S)-1-Benzyl-2-oxo-azepan-3-ylamino)-methyl...)
Show SMILES O=C1[C@H](CCCCN1Cc1ccccc1)NCc1cncn1Cc1ccc(cc1)C#N
Show InChI InChI=1S/C25H27N5O/c26-14-20-9-11-22(12-10-20)18-30-19-27-15-23(30)16-28-24-8-4-5-13-29(25(24)31)17-21-6-2-1-3-7-21/h1-3,6-7,9-12,15,19,24,28H,4-5,8,13,16-18H2/t24-/m0/s1
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MMDB

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Similars
PubMed
n/an/a 8n/an/an/an/an/an/a



Institut de Recherches Servier

Curated by ChEMBL


Assay Description
Inhibition of farnesyltransferase

Bioorg Med Chem Lett 14: 767-71 (2004)


BindingDB Entry DOI: 10.7270/Q2348JSW
More data for this
Ligand-Target Pair