BDBM50139575 4-{5-[(2-Benzyl-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-ylamino)-methyl]-imidazol-1-ylmethyl}-benzonitrile::CHEMBL350803

SMILES: O=C1C(Cc2ccccc2CN1Cc1ccccc1)NCc1cncn1Cc1ccc(cc1)C#N

InChI Key: InChIKey=CXLOTEIXOSAUFS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50139575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50139575 (4-{5-[(2-Benzyl-3-oxo-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES O=C1C(Cc2ccccc2CN1Cc1ccccc1)NCc1cncn1Cc1ccc(cc1)C#N Show InChI InChI=1S/C29H27N5O/c30-15-22-10-12-24(13-11-22)19-34-21-31-16-27(34)17-32-28-14-25-8-4-5-9-26(25)20-33(29(28)35)18-23-6-2-1-3-7-23/h1-13,16,21,28,32H,14,17-20H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of farnesyltransferase				Bioorg Med Chem Lett 14: 767-71 (2004) BindingDB Entry DOI: 10.7270/Q2348JSW
					More data for this Ligand-Target Pair