BDBM50139587 4-{5-[(2-Oxo-3-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-ylamino)-methyl]-imidazol-1-ylmethyl}-benzonitrile::CHEMBL165454

SMILES: O=C1C(NCc2cncn2Cc2ccc(cc2)C#N)c2ccccc2CCN1c1ccccc1

InChI Key: InChIKey=VLPFBBPLGMITHP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50139587   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50139587 (4-{5-[(2-Oxo-3-phenyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES O=C1C(NCc2cncn2Cc2ccc(cc2)C#N)c2ccccc2CCN1c1ccccc1 Show InChI InChI=1S/C28H25N5O/c29-16-21-10-12-22(13-11-21)19-32-20-30-17-25(32)18-31-27-26-9-5-4-6-23(26)14-15-33(28(27)34)24-7-2-1-3-8-24/h1-13,17,20,27,31H,14-15,18-19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of farnesyltransferase				Bioorg Med Chem Lett 14: 767-71 (2004) BindingDB Entry DOI: 10.7270/Q2348JSW
					More data for this Ligand-Target Pair