Found 12 hits for monomerid = 50139896 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Oligopeptide transporter, kidney isoform
(Rattus norvegicus) | BDBM50139896
((6R,7R)-7-((R)-2-Amino-2-phenyl-acetylamino)-3-met...)Show SMILES CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c1ccccc1)C2=O)C(O)=O |r,t:1| Show InChI InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 | PDB
Reactome pathway KEGG
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| Article PubMed
| 4.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Hospital
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing LLC-PK1 cells |
Am J Physiol 273: 706-11 (1997)
Article DOI: 10.1152/ajprenal.1997.273.5.f706 BindingDB Entry DOI: 10.7270/Q2N87DND |
More data for this Ligand-Target Pair | |
Solute carrier family 15 member 2
(Homo sapiens (Human)) | BDBM50139896
((6R,7R)-7-((R)-2-Amino-2-phenyl-acetylamino)-3-met...)Show SMILES CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c1ccccc1)C2=O)C(O)=O |r,t:1| Show InChI InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| DrugBank Article PubMed
| 6.82E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical College of Georgia
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake in SKPT cells |
J Biol Chem 270: 25672-7 (1995)
Article DOI: 10.1074/jbc.270.43.25672 BindingDB Entry DOI: 10.7270/Q2H70JP8 |
More data for this Ligand-Target Pair | |
Oligopeptide transporter, kidney isoform
(Rattus norvegicus) | BDBM50139896
((6R,7R)-7-((R)-2-Amino-2-phenyl-acetylamino)-3-met...)Show SMILES CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c1ccccc1)C2=O)C(O)=O |r,t:1| Show InChI InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 | PDB
Reactome pathway KEGG
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| Article PubMed
| 7.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biozentrum of the Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in SKPT cells |
Eur J Pharm Biopharm 59: 17-24 (2004)
Article DOI: 10.1016/j.ejpb.2004.07.008 BindingDB Entry DOI: 10.7270/Q2TT4S7H |
More data for this Ligand-Target Pair | |
Solute carrier family 15 member 2
(Homo sapiens (Human)) | BDBM50139896
((6R,7R)-7-((R)-2-Amino-2-phenyl-acetylamino)-3-met...)Show SMILES CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c1ccccc1)C2=O)C(O)=O |r,t:1| Show InChI InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 | PDB
Reactome pathway KEGG
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| DrugBank Article PubMed
| 7.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Milano
Curated by ChEMBL
| Assay Description Binding affinity to human PepT2 in SKTP cells |
Bioorg Med Chem 19: 4544-51 (2011)
Article DOI: 10.1016/j.bmc.2011.06.027 BindingDB Entry DOI: 10.7270/Q2MP549P |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM50139896
((6R,7R)-7-((R)-2-Amino-2-phenyl-acetylamino)-3-met...)Show SMILES CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c1ccccc1)C2=O)C(O)=O |r,t:1| Show InChI InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 | Reactome pathway KEGG
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| 2.31E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes |
J Pharmacol Exp Ther 290: 672-7 (1999)
BindingDB Entry DOI: 10.7270/Q2H41SJQ |
More data for this Ligand-Target Pair | |
Solute carrier family 15 member 1
(Rattus norvegicus) | BDBM50139896
((6R,7R)-7-((R)-2-Amino-2-phenyl-acetylamino)-3-met...)Show SMILES CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c1ccccc1)C2=O)C(O)=O |r,t:1| Show InChI InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
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| Article PubMed
| 4.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Hospital
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT1-expressing LLC-PK1 cells |
Am J Physiol 273: 706-11 (1997)
Article DOI: 10.1152/ajprenal.1997.273.5.f706 BindingDB Entry DOI: 10.7270/Q2N87DND |
More data for this Ligand-Target Pair | |
Oligopeptide transporter small intestine isoform
(Homo sapiens (Human)) | BDBM50139896
((6R,7R)-7-((R)-2-Amino-2-phenyl-acetylamino)-3-met...)Show SMILES CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c1ccccc1)C2=O)C(O)=O |r,t:1| Show InChI InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 | PDB
Reactome pathway KEGG
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| 1.40E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description Binding affinity against membrane transport protein PEPT1 in human Caco-2 cells |
J Med Chem 48: 4410-9 (2005)
Article DOI: 10.1021/jm048982w BindingDB Entry DOI: 10.7270/Q2Q24116 |
More data for this Ligand-Target Pair | |
Oligopeptide transporter small intestine isoform
(Homo sapiens (Human)) | BDBM50139896
((6R,7R)-7-((R)-2-Amino-2-phenyl-acetylamino)-3-met...)Show SMILES CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c1ccccc1)C2=O)C(O)=O |r,t:1| Show InChI InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 | PDB
Reactome pathway KEGG
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| DrugBank Article PubMed
| 1.44E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biozentrum of the Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in Caco-2 cells |
Eur J Pharm Biopharm 59: 17-24 (2004)
Article DOI: 10.1016/j.ejpb.2004.07.008 BindingDB Entry DOI: 10.7270/Q2TT4S7H |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 8
(Rattus norvegicus) | BDBM50139896
((6R,7R)-7-((R)-2-Amino-2-phenyl-acetylamino)-3-met...)Show SMILES CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c1ccccc1)C2=O)C(O)=O |r,t:1| Show InChI InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 | Reactome pathway KEGG
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| Article PubMed
| n/a | n/a | 6.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cells |
Life Sci 70: 1861-74 (2002)
Article DOI: 10.1016/s0024-3205(02)01500-x BindingDB Entry DOI: 10.7270/Q2SN0CV2 |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM50139896
((6R,7R)-7-((R)-2-Amino-2-phenyl-acetylamino)-3-met...)Show SMILES CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c1ccccc1)C2=O)C(O)=O |r,t:1| Show InChI InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 | Reactome pathway KEGG
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| Article PubMed
| n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells |
Life Sci 70: 1861-74 (2002)
Article DOI: 10.1016/s0024-3205(02)01500-x BindingDB Entry DOI: 10.7270/Q2SN0CV2 |
More data for this Ligand-Target Pair | |
Oligopeptide transporter small intestine isoform
(Homo sapiens (Human)) | BDBM50139896
((6R,7R)-7-((R)-2-Amino-2-phenyl-acetylamino)-3-met...)Show SMILES CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c1ccccc1)C2=O)C(O)=O |r,t:1| Show InChI InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 | PDB
Reactome pathway KEGG
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| DrugBank Article PubMed
| n/a | n/a | 5.20E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California San Francisco
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 25000 uM) in PEPT1-expressing CHO cells |
Pharm Res 13: 1631-4 (1996)
Article DOI: 10.1023/a:1016476220296 BindingDB Entry DOI: 10.7270/Q2TM7DZF |
More data for this Ligand-Target Pair | |
Oligopeptide transporter small intestine isoform
(Homo sapiens (Human)) | BDBM50139896
((6R,7R)-7-((R)-2-Amino-2-phenyl-acetylamino)-3-met...)Show SMILES CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c1ccccc1)C2=O)C(O)=O |r,t:1| Show InChI InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 | PDB
Reactome pathway KEGG
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| DrugBank Article PubMed
| n/a | n/a | 1.37E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Michigan
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 20 uM) in PEPT1-expressing CHO cells |
J Pharm Sci 88: 347-50 (1999)
Article DOI: 10.1021/js980132e BindingDB Entry DOI: 10.7270/Q22V2H6H |
More data for this Ligand-Target Pair | |