BDBM50139915 Ac-(Glu-Ala-Glu-Lys)-Leu-Arg-Lys-Leu-Nle-Asp-Ile-Ile-NH2::CHEMBL384468

SMILES: CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)C(CCCCC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCCCNC(=O)CC[C@@H](NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N1)C(C)C)[C@@H](C)CC)C(N)=O

InChI Key: InChIKey=JJHCCLAYRAGSDK-YBLFHGFSSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50139915   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50139915 (Ac-(Glu-Ala-Glu-Lys)-Leu-Arg-Lys-Leu-Nle-Asp-Ile-I...) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)C(CCCCC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCCCNC(=O)CC[C@@H](NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N1)C(C)C)[C@@H](C)CC)C(N)=O Show InChI InChI=1S/C68H118N18O19/c1-11-37(7)55(57(71)95)85-67(105)56(38(8)12-2)86-66(104)49(34-54(93)94)83-59(97)41(36(5)6)20-13-14-24-50(88)47(32-35(3)4)82-62(100)42(21-15-17-29-69)79-61(99)44(23-19-31-75-68(72)73)81-65(103)48(33-51(70)89)84-63(101)43-22-16-18-30-74-52(90)27-25-45(77-40(10)87)60(98)76-39(9)58(96)78-46(64(102)80-43)26-28-53(91)92/h35-39,41-49,55-56H,11-34,69H2,1-10H3,(H2,70,89)(H2,71,95)(H,74,90)(H,76,98)(H,77,87)(H,78,96)(H,79,99)(H,80,102)(H,81,103)(H,82,100)(H,83,97)(H,84,101)(H,85,105)(H,86,104)(H,91,92)(H,93,94)(H4,72,73,75)/t37-,38-,39-,41?,42-,43-,44-,45+,46-,47-,48-,49-,55-,56-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity at human CRF1 receptor (CRFR1) on HeLA cell membranes.				J Med Chem 47: 1075-8 (2004) Article DOI: 10.1021/jm034180+ BindingDB Entry DOI: 10.7270/Q28P5ZXK
					More data for this Ligand-Target Pair