BDBM50139916 Ac-(Glu-Ala-His-Lys)-Gln-Arg-Lys-Leu-Nle-Glu-Ile-Ile-NH2::CHEMBL266422

SMILES: CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)C(CCCCC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCCNC(=O)CC[C@@H](NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)[C@@H](C)CC)C(N)=O

InChI Key: InChIKey=TZDHUJRXZVUNBQ-GDXYJMFCSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50139916   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50139916 (Ac-(Glu-Ala-His-Lys)-Gln-Arg-Lys-Leu-Nle-Glu-Ile-I...) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)C(CCCCC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCCNC(=O)CC[C@@H](NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)[C@@H](C)CC)C(N)=O Show InChI InChI=1S/C71H122N20O17/c1-11-40(7)58(60(74)98)90-70(108)59(41(8)12-2)91-68(106)51(27-30-57(96)97)83-62(100)45(39(5)6)20-13-14-24-54(93)52(34-38(3)4)88-66(104)46(21-15-17-31-72)84-65(103)48(23-19-33-79-71(75)76)85-67(105)50(25-28-55(73)94)87-64(102)47-22-16-18-32-78-56(95)29-26-49(82-43(10)92)63(101)81-42(9)61(99)89-53(69(107)86-47)35-44-36-77-37-80-44/h36-42,45-53,58-59H,11-35,72H2,1-10H3,(H2,73,94)(H2,74,98)(H,77,80)(H,78,95)(H,81,101)(H,82,92)(H,83,100)(H,84,103)(H,85,105)(H,86,107)(H,87,102)(H,88,104)(H,89,99)(H,90,108)(H,91,106)(H,96,97)(H4,75,76,79)/t40-,41-,42-,45?,46-,47-,48-,49+,50-,51-,52-,53-,58-,59-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity at human CRF1 receptor (CRFR1) on HeLA cell membranes.				J Med Chem 47: 1075-8 (2004) Article DOI: 10.1021/jm034180+ BindingDB Entry DOI: 10.7270/Q28P5ZXK
					More data for this Ligand-Target Pair