BDBM50140043 CHEMBL3765529
SMILES: O=C(NCc1ccccc1)[C@H](CCCCNC1CC1c1ccccc1)NC(=O)c1ccc(cc1)-c1ccccc1
InChI Key: InChIKey=CEVVHHOKZMIXGC-OMYKBPHGSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50140043 (CHEMBL3765529) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
Waseda University Curated by ChEMBL | Assay Description Inhibition of human LSD1 using H3K4 peptide as substrate by peroxidase-coupled assay | Bioorg Med Chem Lett 26: 1193-5 (2016) BindingDB Entry DOI: 10.7270/Q2833TWV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1B (Homo sapiens (Human)) | BDBM50140043 (CHEMBL3765529) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Waseda University Curated by ChEMBL | Assay Description Inhibition of recombinant human LSD2 using H3K4 peptide as substrate assessed as decrease in H3K4 demethylation after 1 hr by mass spectroscopic anal... | Bioorg Med Chem Lett 26: 1193-5 (2016) BindingDB Entry DOI: 10.7270/Q2833TWV | |||||||||||
More data for this Ligand-Target Pair |