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BDBM50140220 1-(4-Chloro-phenyl)-2-(2,4-dichloro-phenyl)-1H-imidazole-4-carboxylic acid piperidin-1-ylamide::CHEMBL15399

SMILES: Clc1ccc(cc1)-n1cc(nc1-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1

InChI Key: InChIKey=CPZFFCWPBSKKAF-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50140220   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50140220
PNG
(1-(4-Chloro-phenyl)-2-(2,4-dichloro-phenyl)-1H-imi...)
Show SMILES Clc1ccc(cc1)-n1cc(nc1-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C21H19Cl3N4O/c22-14-4-7-16(8-5-14)28-13-19(21(29)26-27-10-2-1-3-11-27)25-20(28)17-9-6-15(23)12-18(17)24/h4-9,12-13H,1-3,10-11H2,(H,26,29)
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23n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
In vitro displacement of CP-55940 binding to human CB1 receptor expressed in CHO cells


J Med Chem 48: 1823-38 (2005)


Article DOI: 10.1021/jm040843r
BindingDB Entry DOI: 10.7270/Q2251JX2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50140220
PNG
(1-(4-Chloro-phenyl)-2-(2,4-dichloro-phenyl)-1H-imi...)
Show SMILES Clc1ccc(cc1)-n1cc(nc1-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C21H19Cl3N4O/c22-14-4-7-16(8-5-14)28-13-19(21(29)26-27-10-2-1-3-11-27)25-20(28)17-9-6-15(23)12-18(17)24/h4-9,12-13H,1-3,10-11H2,(H,26,29)
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85n/an/an/an/an/an/an/an/a



Neurocrine Biosciences Inc.

Curated by ChEMBL


Assay Description
Evaluated for binding affinity towards human Cannabinoid receptor 1


Bioorg Med Chem Lett 14: 1151-4 (2004)


Article DOI: 10.1016/j.bmcl.2003.12.068
BindingDB Entry DOI: 10.7270/Q2MW2GKB
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50140220
PNG
(1-(4-Chloro-phenyl)-2-(2,4-dichloro-phenyl)-1H-imi...)
Show SMILES Clc1ccc(cc1)-n1cc(nc1-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C21H19Cl3N4O/c22-14-4-7-16(8-5-14)28-13-19(21(29)26-27-10-2-1-3-11-27)25-20(28)17-9-6-15(23)12-18(17)24/h4-9,12-13H,1-3,10-11H2,(H,26,29)
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PubMed
542n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
In vitro displacement of CP-55940 binding to human CB2 receptor expressed in CHO cells


J Med Chem 48: 1823-38 (2005)


Article DOI: 10.1021/jm040843r
BindingDB Entry DOI: 10.7270/Q2251JX2
More data for this
Ligand-Target Pair