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BDBM50140228 5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-1H-[1,2,4]triazole-3-carboxylic acid (hexahydro-cyclopenta[c]pyrrol-2-yl)-amide::CHEMBL15877

SMILES: Clc1ccc(cc1)-c1nc(nn1-c1ccc(Cl)cc1Cl)C(=O)NN1CC2CCCC2C1

InChI Key: InChIKey=AKOJRLZCOBTYPX-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140228   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50140228
PNG
(5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-1H-[1,...)
Show SMILES Clc1ccc(cc1)-c1nc(nn1-c1ccc(Cl)cc1Cl)C(=O)NN1CC2CCCC2C1
Show InChI InChI=1S/C22H20Cl3N5O/c23-16-6-4-13(5-7-16)21-26-20(27-30(21)19-9-8-17(24)10-18(19)25)22(31)28-29-11-14-2-1-3-15(14)12-29/h4-10,14-15H,1-3,11-12H2,(H,28,31)
PDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
164n/an/an/an/an/an/an/an/a



Neurocrine Biosciences Inc.

Curated by ChEMBL


Assay Description
Evaluated for binding affinity towards human Cannabinoid receptor 1


Bioorg Med Chem Lett 14: 1151-4 (2004)


Article DOI: 10.1016/j.bmcl.2003.12.068
BindingDB Entry DOI: 10.7270/Q2MW2GKB
More data for this
Ligand-Target Pair