BDBM50140344 CHEMBL3753122

SMILES: COc1ccccc1N1CCN(CC1)c1cc(nc(NCCC(O)=O)n1)-n1nccn1

InChI Key: InChIKey=RKZMTKAZVAECMX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140344   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140344 (CHEMBL3753122) Show SMILES COc1ccccc1N1CCN(CC1)c1cc(nc(NCCC(O)=O)n1)-n1nccn1 Show InChI InChI=1S/C20H24N8O3/c1-31-16-5-3-2-4-15(16)26-10-12-27(13-11-26)17-14-18(28-22-8-9-23-28)25-20(24-17)21-7-6-19(29)30/h2-5,8-9,14H,6-7,10-13H2,1H3,(H,29,30)(H,21,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair