BDBM50140351 CHEMBL3752471

SMILES: OC(=O)CCNc1nc(cc(n1)-n1cc2ccccc2n1)N1CCN(CC1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=WPYJAUVCWNRUBU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140351 (CHEMBL3752471) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1cc2ccccc2n1)N1CCN(CC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C24H23Cl2N7O2/c25-18-6-5-17(13-19(18)26)31-9-11-32(12-10-31)21-14-22(29-24(28-21)27-8-7-23(34)35)33-15-16-3-1-2-4-20(16)30-33/h1-6,13-15H,7-12H2,(H,34,35)(H,27,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair