BDBM50140364 2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-3-carboxylic acid [4-(4-methyl-piperazin-1-yl)-phenyl]-amide::CHEMBL21064

SMILES: CN1CCN(CC1)c1ccc(NC(=O)c2cc(C)nn2-c2ccc3cc(Cl)ccc3c2)cc1

InChI Key: InChIKey=CONLBRJPCFRHHU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140364   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50140364 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES CN1CCN(CC1)c1ccc(NC(=O)c2cc(C)nn2-c2ccc3cc(Cl)ccc3c2)cc1 Show InChI InChI=1S/C26H26ClN5O/c1-18-15-25(32(29-18)24-8-4-19-16-21(27)5-3-20(19)17-24)26(33)28-22-6-9-23(10-7-22)31-13-11-30(2)12-14-31/h3-10,15-17H,11-14H2,1-2H3,(H,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	166	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair