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BDBM50140379 2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-3-carboxylic acid (2-fluoro-4-pyridin-3-yl-phenyl)-amide::CHEMBL20815

SMILES: Cc1cc(C(=O)Nc2ccc(cc2F)-c2cccnc2)n(n1)-c1ccc2cc(Cl)ccc2c1

InChI Key: InChIKey=QGYSPMJVNPJPBH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140379   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50140379
PNG
(2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...)
Show SMILES Cc1cc(C(=O)Nc2ccc(cc2F)-c2cccnc2)n(n1)-c1ccc2cc(Cl)ccc2c1
Show InChI InChI=1S/C26H18ClFN4O/c1-16-11-25(32(31-16)22-8-5-17-12-21(27)7-4-18(17)13-22)26(33)30-24-9-6-19(14-23(24)28)20-3-2-10-29-15-20/h2-15H,1H3,(H,30,33)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 92n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human Coagulation factor X


Bioorg Med Chem Lett 14: 1221-7 (2004)


Article DOI: 10.1016/j.bmcl.2003.12.053
BindingDB Entry DOI: 10.7270/Q2VD6XV5
More data for this
Ligand-Target Pair