BDBM50140405 2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-3-carboxylic acid (4-piperidin-1-yl-phenyl)-amide::CHEMBL20708

SMILES: Cc1cc(C(=O)Nc2ccc(cc2)N2CCCCC2)n(n1)-c1ccc2cc(Cl)ccc2c1

InChI Key: InChIKey=PJSHSVCQMVWYTF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50140405 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2)N2CCCCC2)n(n1)-c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C26H25ClN4O/c1-18-15-25(31(29-18)24-10-6-19-16-21(27)7-5-20(19)17-24)26(32)28-22-8-11-23(12-9-22)30-13-3-2-4-14-30/h5-12,15-17H,2-4,13-14H2,1H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair