BDBM50140414 1-(3-Fluoro-naphthalen-2-yl)-1H-tetrazole-5-carboxylic acid [2-fluoro-4-(imino-piperidin-1-yl-methyl)-phenyl]-amide::CHEMBL416181

SMILES: Fc1cc(ccc1NC(=O)c1nnnn1-c1cc2ccccc2cc1F)C(=N)N1CCCCC1

InChI Key: InChIKey=MTYNQJDXFWWIDO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50140414 (1-(3-Fluoro-naphthalen-2-yl)-1H-tetrazole-5-carbox...) Show SMILES Fc1cc(ccc1NC(=O)c1nnnn1-c1cc2ccccc2cc1F)C(=N)N1CCCCC1 Show InChI InChI=1S/C24H21F2N7O/c25-18-13-17(22(27)32-10-4-1-5-11-32)8-9-20(18)28-24(34)23-29-30-31-33(23)21-14-16-7-3-2-6-15(16)12-19(21)26/h2-3,6-9,12-14,27H,1,4-5,10-11H2,(H,28,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against human coagulation factor X				Bioorg Med Chem Lett 14: 1229-34 (2004) Article DOI: 10.1016/j.bmcl.2003.12.054 BindingDB Entry DOI: 10.7270/Q2QN6664
					More data for this Ligand-Target Pair