BDBM50140417 2-(3-Fluoro-naphthalen-2-yl)-5-methyl-2H-pyrazole-3-carboxylic acid [2-fluoro-4-(imino-pyrrolidin-1-yl-methyl)-phenyl]-amide::CHEMBL21179

SMILES: Cc1cc(C(=O)Nc2ccc(cc2F)C(=N)N2CCCC2)n(n1)-c1cc2ccccc2cc1F

InChI Key: InChIKey=LQHYFMKRZYGPBR-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140417   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50140417 (2-(3-Fluoro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2F)C(=N)N2CCCC2)n(n1)-c1cc2ccccc2cc1F Show InChI InChI=1S/C26H23F2N5O/c1-16-12-24(33(31-16)23-15-18-7-3-2-6-17(18)13-21(23)28)26(34)30-22-9-8-19(14-20(22)27)25(29)32-10-4-5-11-32/h2-3,6-9,12-15,29H,4-5,10-11H2,1H3,(H,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity for human Coagulation factor X				Bioorg Med Chem Lett 14: 1229-34 (2004) Article DOI: 10.1016/j.bmcl.2003.12.054 BindingDB Entry DOI: 10.7270/Q2QN6664
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140417 (2-(3-Fluoro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2F)C(=N)N2CCCC2)n(n1)-c1cc2ccccc2cc1F Show InChI InChI=1S/C26H23F2N5O/c1-16-12-24(33(31-16)23-15-18-7-3-2-6-17(18)13-21(23)28)26(34)30-22-9-8-19(14-20(22)27)25(29)32-10-4-5-11-32/h2-3,6-9,12-15,29H,4-5,10-11H2,1H3,(H,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity for human Coagulation factor X				Bioorg Med Chem Lett 14: 1229-34 (2004) Article DOI: 10.1016/j.bmcl.2003.12.054 BindingDB Entry DOI: 10.7270/Q2QN6664
					More data for this Ligand-Target Pair