BDBM50140429 1-(6-Chloro-naphthalen-2-yl)-1H-tetrazole-5-carboxylic acid [2-fluoro-4-(imino-piperidin-1-yl-methyl)-phenyl]-amide::CHEMBL21562

SMILES: Fc1cc(ccc1NC(=O)c1nnnn1-c1ccc2cc(Cl)ccc2c1)C(=N)N1CCCCC1

InChI Key: InChIKey=SNUAYEFIXDPRIZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140429   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50140429 (1-(6-Chloro-naphthalen-2-yl)-1H-tetrazole-5-carbox...) Show SMILES Fc1cc(ccc1NC(=O)c1nnnn1-c1ccc2cc(Cl)ccc2c1)C(=N)N1CCCCC1 Show InChI InChI=1S/C24H21ClFN7O/c25-18-7-4-16-13-19(8-5-15(16)12-18)33-23(29-30-31-33)24(34)28-21-9-6-17(14-20(21)26)22(27)32-10-2-1-3-11-32/h4-9,12-14,27H,1-3,10-11H2,(H,28,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against human coagulation factor X				Bioorg Med Chem Lett 14: 1229-34 (2004) Article DOI: 10.1016/j.bmcl.2003.12.054 BindingDB Entry DOI: 10.7270/Q2QN6664
					More data for this Ligand-Target Pair