BDBM50140442 1-(6-Chloro-naphthalen-2-yl)-1H-tetrazole-5-carboxylic acid [2-fluoro-4-(imino-pyrrolidin-1-yl-methyl)-phenyl]-amide::CHEMBL20496

SMILES: Fc1cc(ccc1NC(=O)c1nnnn1-c1ccc2cc(Cl)ccc2c1)C(=N)N1CCCC1

InChI Key: InChIKey=CWEIGYKXFPMECB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140442   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50140442 (1-(6-Chloro-naphthalen-2-yl)-1H-tetrazole-5-carbox...) Show SMILES Fc1cc(ccc1NC(=O)c1nnnn1-c1ccc2cc(Cl)ccc2c1)C(=N)N1CCCC1 Show InChI InChI=1S/C23H19ClFN7O/c24-17-6-3-15-12-18(7-4-14(15)11-17)32-22(28-29-30-32)23(33)27-20-8-5-16(13-19(20)25)21(26)31-9-1-2-10-31/h3-8,11-13,26H,1-2,9-10H2,(H,27,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against human coagulation factor X				Bioorg Med Chem Lett 14: 1229-34 (2004) Article DOI: 10.1016/j.bmcl.2003.12.054 BindingDB Entry DOI: 10.7270/Q2QN6664
					More data for this Ligand-Target Pair