BDBM50140574 CHEMBL3753391

SMILES: OC(=O)CCNc1nc(cc(n1)-n1cccn1)N1CCc2ccccc2CC1

InChI Key: InChIKey=HBCNJLXHGDFTOZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140574 (CHEMBL3753391) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1cccn1)N1CCc2ccccc2CC1 Show InChI InChI=1S/C20H22N6O2/c27-19(28)6-10-21-20-23-17(14-18(24-20)26-11-3-9-22-26)25-12-7-15-4-1-2-5-16(15)8-13-25/h1-5,9,11,14H,6-8,10,12-13H2,(H,27,28)(H,21,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair