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BDBM50140577 CHEMBL3753326

SMILES: OC(=O)CCNc1nc(cc(n1)-n1cccn1)N1CCN(CC1)c1ccccn1

InChI Key: InChIKey=HVWFFWGMCSVGGV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140577   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 6B


(Homo sapiens (Human))
BDBM50140577
PNG
(CHEMBL3753326)
Show SMILES OC(=O)CCNc1nc(cc(n1)-n1cccn1)N1CCN(CC1)c1ccccn1
Show InChI InChI=1S/C19H22N8O2/c28-18(29)5-8-21-19-23-16(14-17(24-19)27-9-3-7-22-27)26-12-10-25(11-13-26)15-4-1-2-6-20-15/h1-4,6-7,9,14H,5,8,10-13H2,(H,28,29)(H,21,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay


Bioorg Med Chem Lett 26: 721-5 (2016)


BindingDB Entry DOI: 10.7270/Q2P55QC2
More data for this
Ligand-Target Pair