BDBM50140656 CHEMBL26552::[6-(4-Ethoxy-phenyl)-4,5,7-trimethyl-6H-pyrrolo[3,4-d]pyridazin-1-yl]-phenyl-amine

SMILES: CCOc1ccc(cc1)-n1c(C)c2c(C)nnc(Nc3ccccc3)c2c1C

InChI Key: InChIKey=IIXUZNNUQDOARN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140656   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50140656 (CHEMBL26552 | [6-(4-Ethoxy-phenyl)-4,5,7-trimethyl...) Show SMILES CCOc1ccc(cc1)-n1c(C)c2c(C)nnc(Nc3ccccc3)c2c1C Show InChI InChI=1S/C23H24N4O/c1-5-28-20-13-11-19(12-14-20)27-16(3)21-15(2)25-26-23(22(21)17(27)4)24-18-9-7-6-8-10-18/h6-14H,5H2,1-4H3,(H,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentin				Bioorg Med Chem Lett 14: 1295-8 (2004) Article DOI: 10.1016/j.bmcl.2003.12.036 BindingDB Entry DOI: 10.7270/Q26Q1WPT
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