BDBM50140659 CHEMBL287371::[6-(4-Ethoxy-phenyl)-4,5,7-trimethyl-6H-pyrrolo[3,4-d]pyridazin-1-yl]-methyl-amine

SMILES: CCOc1ccc(cc1)-n1c(C)c2c(C)nnc(NC)c2c1C

InChI Key: InChIKey=FASKULMRUUGIHB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140659   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50140659 (CHEMBL287371 | [6-(4-Ethoxy-phenyl)-4,5,7-trimethy...) Show SMILES CCOc1ccc(cc1)-n1c(C)c2c(C)nnc(NC)c2c1C Show InChI InChI=1S/C18H22N4O/c1-6-23-15-9-7-14(8-10-15)22-12(3)16-11(2)20-21-18(19-5)17(16)13(22)4/h7-10H,6H2,1-5H3,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentin				Bioorg Med Chem Lett 14: 1295-8 (2004) Article DOI: 10.1016/j.bmcl.2003.12.036 BindingDB Entry DOI: 10.7270/Q26Q1WPT
					More data for this Ligand-Target Pair