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BDBM50140677 CHEMBL3752551

SMILES: OC(=O)CCNc1nc(cc(n1)-n1cccn1)N1CCN(CC1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=VCZLBIVEIHMMFZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140677   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 6B


(Homo sapiens (Human))
BDBM50140677
PNG
(CHEMBL3752551)
Show SMILES OC(=O)CCNc1nc(cc(n1)-n1cccn1)N1CCN(CC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H21Cl2N7O2/c21-15-3-2-14(12-16(15)22)27-8-10-28(11-9-27)17-13-18(29-7-1-5-24-29)26-20(25-17)23-6-4-19(30)31/h1-3,5,7,12-13H,4,6,8-11H2,(H,30,31)(H,23,25,26)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 740n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay


Bioorg Med Chem Lett 26: 721-5 (2016)


BindingDB Entry DOI: 10.7270/Q2P55QC2
More data for this
Ligand-Target Pair