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BDBM50140678 CHEMBL3752769

SMILES: OC(=O)CCNc1nc(cc(n1)-n1cccn1)N1CCc2ccccc2C1

InChI Key: InChIKey=IEBVIQNPXBCZAK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140678   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 6B


(Homo sapiens (Human))
BDBM50140678
PNG
(CHEMBL3752769)
Show SMILES OC(=O)CCNc1nc(cc(n1)-n1cccn1)N1CCc2ccccc2C1
Show InChI InChI=1S/C19H20N6O2/c26-18(27)6-9-20-19-22-16(12-17(23-19)25-10-3-8-21-25)24-11-7-14-4-1-2-5-15(14)13-24/h1-5,8,10,12H,6-7,9,11,13H2,(H,26,27)(H,20,22,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 490n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay


Bioorg Med Chem Lett 26: 721-5 (2016)


BindingDB Entry DOI: 10.7270/Q2P55QC2
More data for this
Ligand-Target Pair