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BDBM50140682 CHEMBL3752967

SMILES: OC(=O)CCNc1nc(cc(n1)-n1nccn1)N1CCN(CC1)c1ccccn1

InChI Key: InChIKey=WUXKGZDUHSQLHM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140682   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 6B


(Homo sapiens (Human))
BDBM50140682
PNG
(CHEMBL3752967)
Show SMILES OC(=O)CCNc1nc(cc(n1)-n1nccn1)N1CCN(CC1)c1ccccn1
Show InChI InChI=1S/C18H21N9O2/c28-17(29)4-6-20-18-23-15(13-16(24-18)27-21-7-8-22-27)26-11-9-25(10-12-26)14-3-1-2-5-19-14/h1-3,5,7-8,13H,4,6,9-12H2,(H,28,29)(H,20,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay


Bioorg Med Chem Lett 26: 721-5 (2016)


BindingDB Entry DOI: 10.7270/Q2P55QC2
More data for this
Ligand-Target Pair