BDBM50140696 CHEMBL3752613::US10383880, Example 16

SMILES: OC(CN(Cc1ccco1)S(=O)(=O)C1CC1)Cn1c2ccccc2c2ccccc12

InChI Key: InChIKey=VASICDYHZRSWQB-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140696   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140696 (CHEMBL3752613 | US10383880, Example 16) Show SMILES OC(CN(Cc1ccco1)S(=O)(=O)C1CC1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C23H24N2O4S/c26-17(14-24(16-18-6-5-13-29-18)30(27,28)19-11-12-19)15-25-22-9-3-1-7-20(22)21-8-2-4-10-23(21)25/h1-10,13,17,19,26H,11-12,14-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.67E+3	n/a	n/a	n/a	n/a
Synchronicity US Patent					Assay Description Per2 Assay for Evaluating the Potency of Test Compounds.				US Patent US10383880 (2019) BindingDB Entry DOI: 10.7270/Q2J67K8X
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140696 (CHEMBL3752613 | US10383880, Example 16) Show SMILES OC(CN(Cc1ccco1)S(=O)(=O)C1CC1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C23H24N2O4S/c26-17(14-24(16-18-6-5-13-29-18)30(27,28)19-11-12-19)15-25-22-9-3-1-7-20(22)21-8-2-4-10-23(21)25/h1-10,13,17,19,26H,11-12,14-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	557	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair