BDBM50140698 CHEMBL3753223::US10383880, Example 13

SMILES: CC(C)CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)Cc1ccco1

InChI Key: InChIKey=LXEDMOOLYSISPT-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140698 (CHEMBL3753223 | US10383880, Example 13) Show SMILES CC(C)CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)Cc1ccco1 Show InChI InChI=1S/C24H28N2O4S/c1-18(2)17-31(28,29)25(16-20-8-7-13-30-20)14-19(27)15-26-23-11-5-3-9-21(23)22-10-4-6-12-24(22)26/h3-13,18-19,27H,14-17H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	454	n/a	n/a	n/a	n/a
Synchronicity US Patent					Assay Description Per2 Assay for Evaluating the Potency of Test Compounds.				US Patent US10383880 (2019) BindingDB Entry DOI: 10.7270/Q2J67K8X
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140698 (CHEMBL3753223 | US10383880, Example 13) Show SMILES CC(C)CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)Cc1ccco1 Show InChI InChI=1S/C24H28N2O4S/c1-18(2)17-31(28,29)25(16-20-8-7-13-30-20)14-19(27)15-26-23-11-5-3-9-21(23)22-10-4-6-12-24(22)26/h3-13,18-19,27H,14-17H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	361	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair