BDBM50140700 CHEMBL3754797::US10383880, Example 85

SMILES: OC(CN(Cc1ccco1)S(=O)(=O)C1CCOC1)Cn1c2ccccc2c2ccccc12

InChI Key: InChIKey=YMACIXCRDONPNU-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140700   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140700 (CHEMBL3754797 | US10383880, Example 85) Show SMILES OC(CN(Cc1ccco1)S(=O)(=O)C1CCOC1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C24H26N2O5S/c27-18(15-26-23-9-3-1-7-21(23)22-8-2-4-10-24(22)26)14-25(16-19-6-5-12-31-19)32(28,29)20-11-13-30-17-20/h1-10,12,18,20,27H,11,13-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	n/a	n/a	510	n/a	n/a	n/a	n/a
Synchronicity US Patent					Assay Description Per2 Assay for Evaluating the Potency of Test Compounds.				US Patent US10383880 (2019) BindingDB Entry DOI: 10.7270/Q2J67K8X
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140700 (CHEMBL3754797 | US10383880, Example 85) Show SMILES OC(CN(Cc1ccco1)S(=O)(=O)C1CCOC1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C24H26N2O5S/c27-18(15-26-23-9-3-1-7-21(23)22-8-2-4-10-24(22)26)14-25(16-19-6-5-12-31-19)32(28,29)20-11-13-30-17-20/h1-10,12,18,20,27H,11,13-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair