BDBM50140733 (3aR,7aR)-1-(1-Cyclooctyl-piperidin-4-yl)-octahydro-benzoimidazol-2-one::CHEMBL284217

SMILES: O=C1N[C@@H]2CCCC[C@H]2N1C1CCN(CC1)C1CCCCCCC1

InChI Key: InChIKey=SIKXVXOGIUHXJZ-RTBURBONSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140733   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50140733 ((3aR,7aR)-1-(1-Cyclooctyl-piperidin-4-yl)-octahydr...) Show SMILES O=C1N[C@@H]2CCCC[C@H]2N1C1CCN(CC1)C1CCCCCCC1 Show InChI InChI=1S/C20H35N3O/c24-20-21-18-10-6-7-11-19(18)23(20)17-12-14-22(15-13-17)16-8-4-2-1-3-5-9-16/h16-19H,1-15H2,(H,21,24)/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. Curated by ChEMBL					Assay Description Binding affinity towards Nociceptin/orphanin FQ (N/OFQ) receptor from recombinant HEK293 cell membranes was determined using binding assay				Bioorg Med Chem Lett 14: 1347-51 (2004) Article DOI: 10.1016/j.bmcl.2003.11.083 BindingDB Entry DOI: 10.7270/Q2QJ7HW5
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50140733 ((3aR,7aR)-1-(1-Cyclooctyl-piperidin-4-yl)-octahydr...) Show SMILES O=C1N[C@@H]2CCCC[C@H]2N1C1CCN(CC1)C1CCCCCCC1 Show InChI InChI=1S/C20H35N3O/c24-20-21-18-10-6-7-11-19(18)23(20)17-12-14-22(15-13-17)16-8-4-2-1-3-5-9-16/h16-19H,1-15H2,(H,21,24)/t18-,19-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor mu 1 using [3H]- diprenophine as radioligand from membrane preparations of recombinant HEK293 cells				Bioorg Med Chem Lett 14: 1347-51 (2004) Article DOI: 10.1016/j.bmcl.2003.11.083 BindingDB Entry DOI: 10.7270/Q2QJ7HW5
					More data for this Ligand-Target Pair